The two I can think of right now:

-Indiana Jones 5 (Indy 4 was OK, not great, and not the horrible abomination some make it out to be, in my opinion...Nuking The Fridge and Space Aliens are two big leaps of faith, and pretty implausible...but to me, if the guy can survive the Ark of the Covenant's Holym Demons, getting his heart torn out while beating and having it placed back in, no problem, and curing his dad Sean Connery with the Holy Grail, I can take that leap. That being said, Indy needs one more movie, I think, to send him off in style...Harrison Ford's still willing, and I'd like to see it happen before it's too late--I've always hoped Indy would go on one of the Ancient Greek quests, he's already done my other mythological favorite with the Holy Grail and getting the Ark was a great one as well...how about "Indiana Jones and the Quest for the Medusa's Head" or "Indiana Jones and the Labrynth of the Minotaur?" THAT would be a way to go out!)

-Star Trek 12 (OBviously it's coming out next year...I hear they might remake the TOS episode "Where No Man Has Gone Before" in part, where Kirk's friend Gary Mitchell gets god-like powers and goes mad with power...and I think that'd be a great way to go--but I want the Klingons back, damnit, as bad guys! Maybe hunting down the Vulcans!)