The issue with that quote is that his book was published in 1978. I can't verify when the Edi Birsan popularized the Lepanto, and it's conceivable that it was before this book was published. This is a move that changed the landscape for Italy.
But things have changed. In that time, apart from face to face games the game could only be played by mail. These took a long time, there was less sample size. Recently, games can be played online, on mobile phones, over email, etc. The amount of games being played has increased exponentially.
So, now, people have more experience to draw from. It's not just about the Lepanto, but the game is designed in such that nobody has an inherent advantage because the mechanics of the game - alliances and power dynamics are all adjusted to match the results in the game. Italy always has a chance. I would say even, based on where this power's builds are located it has the easiest path to a solo once it has some momentum, even more so than Russia.