Of course it can.
http://webdiplomacy.net/board.php?
gameID=186635 <- I fuck up in this one, but still end up part of the draw
http://webdiplomacy.net/board.php?
gameID=184054 <- I win this one
I'd only ever open against France if I'm reasonably sure Austria has no friends and is willing to remain neutral. Regardless of circumstances, France (or England) WILL eventually attack you, and typically with more power than you'll have any chance of responding to if you open against Austria or Turkey. In light of that, I find that it's an excellent use of your time to nip France in the bud while the eastern powers do their thing. Marseilles and Iberia are rather easy to hold on to as well, unlike anything you'd get in the Balkans.
I wouldn't claim to be a particularly experienced or talented player, though.